Gates has pledged to donate $1 billion to the United Nations World Health Organization, in what his foundation says is a symbolic step to ensure the vaccine is administered to millions of people.
The billionaire philanthropist is among a group of well-known figures who have donated money to the WHO, including former US President Bill Clinton, former British Prime Minister David Cameron and Australian Prime Minister Julia Gillard.
The announcement of the donation comes as the global health agency is battling to halt the pandemic in countries across Africa, Asia and Latin America, as well as the United States.
President Donald Trump has pledged that the US will continue to use military force to bring peace to Africa.
Gates has long been an outspoken critic of the US military presence in the region.
Last year, he said it was “time for us to stop being the bad guys and start being the good guys”.
“The United States has a responsibility to work with the UN to protect and support people in need,” Gates wrote in an op-ed in The Wall Street Journal.
“We must work together to prevent and eradicate polio in the world.”
Earlier this month, Gates and other high-profile figures, including Indian Prime Minister Narendra Modi, announced they would join forces to develop an international polio vaccine that could reach a majority of the world’s population by 2025.